Overview of Emphysema

Emphysema is a chronic lung condition that causes damage to the alveoli (air sacs) in the lungs. It is a type of chronic obstructive pulmonary disease (COPD) that results in difficulty breathing, as the damaged alveoli lose their elasticity and become less effective in oxygen exchange. Emphysema disease is characterised by shortness of breath and is often caused by smoking or long term exposure to airborne irritants.

Types of Emphysema

There are two main types of emphysema:


Centriacinar emphysema: This primarily affects the central parts of the lungs and is often linked to smoking.

Panacinar emphysema: Involves the entire alveolar unit and is typically associated with genetic conditions such as alpha-1 antitrypsin deficiency.

Symptoms of Emphysema

  • Shortness of breath: Struggling for breath, especially during physical exertion.
  • Chronic cough: Persistent coughing with or without mucus.
  • Wheezing: A whistling sound while breathing.
  • Fatigue: Feeling constantly tired or weak.
  • Barrel chest: Chest enlargement in advanced stages due to lung over-inflation.
  • Cyanosis: Bluish tint to lips or fingers from lack of oxygen.

Causes of Emphysema

  • Smoking: The primary cause of emphysema in the majority of cases.
  • Air pollution: Long term exposure to environmental pollutants.
  • Genetic factors: Inherited conditions like alpha-1 antitrypsin deficiency increase susceptibility.

Complications in Emphysema

  • Respiratory infections: Such as pneumonia, more common due to weakened lungs.
  • Lung collapse: Rupture of weakened alveoli leading to pneumothorax.
  • Heart problems: Strain on the heart, particularly the right side, due to low oxygen levels.
  • Increased cancer risk: Emphysema raises the likelihood of developing lung cancer in smokers.

Risk Factors of Emphysema

  • Smoking: The number one risk factor for emphysema.
  • Age: Risk increases with age, particularly after 40 years.
  • Exposure to lung irritants: Includes workplace dust, fumes and secondhand smoke.
  • Family history: Having a relative with emphysema or alpha-1 antitrypsin deficiency.

Preventions of Emphysema

  • Quit smoking: Stopping smoking significantly slows disease progression.
  • Avoid irritants: Reduce exposure to pollutants and chemicals in the air.
  • Regular physical activity: Helps improve lung function and overall health.
  • Vaccinations: Protect yourself from flu and pneumonia through vaccinations.

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